Background:

The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.

Applications:

ELISA, IHC

Name of antibody:

ASPP1

Immunogen:

Synthetic peptide of human ASPP1

Full name:

Apoptosis-stimulating of p53 protein 1

Synonyms：

PPP1R13B, KIAA0771, p53BP2-like, p85

SwissProt:

Q96KQ4

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100