Background:

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs.

Applications:

IHC

Name of antibody:

TAF13

Immunogen:

Synthesized peptide derived from internal of human TAF13.

Full name:

TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa

Synonyms：

TAF2K; TAFII18; TAFII-18; TAF(II)18

SwissProt:

Q15543

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100