Background:

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Applications:

ELISA, IHC

Name of antibody:

ORC4

Immunogen:

Fusion protein of human ORC4

Full name:

origin recognition complex subunit 4

Synonyms:

ORC4L; ORC4P

SwissProt:

O43929

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human cervical cancer

IHC Recommend dilution:

40-200