Background:

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

MUTYH

Immunogen:

Fusion protein of human MUTYH

Full name:

mutY homolog (E. coli)

Synonyms：

MYH, CYP2C

SwissProt:

Q9UIF7

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human lung cancer and Human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

60 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

1000-5000