Background:

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Applications:

WB

Name of antibody:

PMS1

Immunogen:

Fusion protein of human PMS1

Full name:

PMS1 homolog 1, mismatch repair system component

Synonyms:

MLH2; PMSL1; hPMS1; HNPCC3

SwissProt:

P54277

WB Predicted band size:

106 kDa

WB Positive control:

HeLa, Jurkat, Molt-4 and HepG2 cells

WB Recommended dilution:

500-2000