Background:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters.

Applications:

WB

Name of antibody:

PRKCA(Ab-657)

Immunogen:

Synthesized non-phosphopeptide derived from human PKC α around the phosphorylation site of tyrosine 657 (F-S-Y(p)-V-N).

Full name:

protein kinase C, alpha

Synonyms：

AAG6; PKCA; PRKACA; PKC-alpha

SwissProt:

P17252

WB Predicted band size:

77 kDa

WB Positive control:

MCF7 cells and Jurkat cells lysates

WB Recommended dilution:

500-3000