IHC Recommend dilution:

50-200

IHC positive control:

Human liver cancer

ELISA Recommended dilution:

5000-10000

SwissProt:

Q13126

Synonyms:

BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249

Full name:

methylthioadenosine phosphorylase

Immunogen:

Fusion protein of human MTAP

Name of antibody:

MTAP

Applications:

ELISA, IHC

Background:

This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.