Background:

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

MEN1

Immunogen:

Synthetic peptide of human MEN1

Full name:

multiple endocrine neoplasia I

Synonyms：

MEAI; SCG2

SwissProt:

O00255

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

68 kDa

WB Positive control:

Raji and Jurkat cell

WB Recommended dilution:

500-2000