Background:

This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, IHC

Name of antibody:

NPL

Immunogen:

Fusion protein of human NPL

Full name:

N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

Synonyms：

NAL; C112; NPL1; C1orf13

SwissProt:

Q9BXD5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100