Background:

Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

PLAG1

Immunogen:

Synthetic peptide of human PLAG1

Full name:

pleiomorphic adenoma gene 1

Synonyms：

PSA; SGPA; ZNF912

SwissProt:

Q6DJT9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

56 kDa

WB Positive control:

Hepg2，A431，Hela and A549 cell lysates

WB Recommended dilution:

500-2000