Background:

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]

Applications:

ELISA, WB, IHC

Name of antibody:

POLD1

Immunogen:

Fusion protein of human POLD1

Full name:

DNA polymerase delta 1, catalytic subunit

Synonyms:

CDC2; MDPL; POLD; CRCS10

SwissProt:

P28340

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

150-300

WB Predicted band size:

124 kDa

WB Positive control:

K562 cell lysate

WB Recommended dilution:

500-2000