Background:

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

Applications:

ELISA, WB, IHC

Name of antibody:

PPBP

Immunogen:

Synthetic peptide of human PPBP

Full name:

pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

Synonyms：

PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III

SwissProt:

P02775

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

14 kDa

WB Positive control:

Human plasma solution

WB Recommended dilution:

1000-5000