Background:

Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.

Applications:

ELISA, WB, IHC

Name of antibody:

TNNC2

Immunogen:

Fusion protein of human TNNC2

Full name:

troponin C2, fast skeletal type

SwissProt:

P02585

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-100

WB Predicted band size:

18 kDa

WB Positive control:

Human muscle tissue lysate

WB Recommended dilution:

500-2000