Background:

This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X.

Applications:

ELISA, IHC

Name of antibody:

PTP4A1

Immunogen:

Fusion protein of human PTP4A1

Full name:

protein tyrosine phosphatase type IVA, member 1

Synonyms:

HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1)

SwissProt:

Q93096

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

30-150