Background:

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

TGM2

Immunogen:

Fusion protein of human TGM2

Full name:

Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

Synonyms：

TG2; TGC; GNAH; G-ALPHA-h

SwissProt:

P21980

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer and human lung cancer

IHC Recommend dilution:

15-50

WB Predicted band size:

77 kDa

WB Positive control:

Lovo and hela cells, human liver cancer and fetal liver tissue

WB Recommended dilution:

200-1000