Background:

This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

TLK2

Immunogen:

Fusion protein of human TLK2

Full name:

tousled like kinase 2

Synonyms:

HsHPK; MRD57; PKU-ALPHA

SwissProt:

Q86UE8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and Human colorectal cancer

IHC Recommend dilution:

50-200