Background:

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'.

Applications:

ELISA, WB, IHC

Name of antibody:

HBE1

Immunogen:

Fusion protein of human HBE1

Full name:

hemoglobin subunit epsilon 1

Synonyms:

HBE

SwissProt:

P02100

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

30-150

WB Predicted band size:

16 kDa

WB Positive control:

Human placenta tissue lysate

WB Recommended dilution:

500-2000