Background:

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Applications:

ELISA, WB

Name of antibody:

PABPC1

Immunogen:

Fusion protein of human PABPC1

Full name:

poly(A) binding protein, cytoplasmic 1

Synonyms：

PAB1; PABP; PABP1; PABPC2; PABPL1

SwissProt:

P11940

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

71 kDa

WB Positive control:

LoVo and Hela cells

WB Recommended dilution:

200-1000