Background:

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains.

Applications:

IHC, IF

Name of antibody:

PDZD2

Immunogen:

Synthesized peptide derived from internal of human PDZD2.

Full name:

PDZ domain containing 2

Synonyms：

AIPC; PIN1; PAPIN; PDZK3

SwissProt:

O15018

IHC positive control:

Human prostate carcinoma tissue

IHC Recommend dilution:

50-100

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500