Background:

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.

Applications:

WB

Name of antibody:

NFKBIB(Phospho-Thr19)

Immunogen:

Peptide sequence around phosphorylation site of Threonine 19 (C-D-S(p)-G-L) derived from Human IkappaB- beta.

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Synonyms：

IKBB; TRIP9

SwissProt:

Q15653

WB Predicted band size:

38 kDa

WB Positive control:

Mouse brain tissue lysates

WB Recommended dilution:

500-1000