Background:

Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.

Applications:

ELISA, IHC

Name of antibody:

UBA52

Immunogen:

Synthetic peptide of human UBA52

Full name:

ubiquitin A-52 residue ribosomal protein fusion product 1

Synonyms:

L40; CEP52; RPL40; HUBCEP52

SwissProt:

P62987

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human breast cancer

IHC Recommend dilution:

40-200