Background:

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).

Applications:

ELISA, IHC

Name of antibody:

UBA6

Immunogen:

Fusion protein of human UBA6

Full name:

ubiquitin-like modifier activating enzyme 6

Synonyms:

E1-L2; MOP-4; UBE1L2

SwissProt:

A0AVT1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

25-100