Background:

The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Applications:

ELISA, IHC

Name of antibody:

NRG1

Immunogen:

Synthetic peptide of human NRG1

Full name:

neuregulin 1

Synonyms:

GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2

SwissProt:

Q02297

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and human thyroid cancer

IHC Recommend dilution:

25-100