Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Applications:

WB

Name of antibody:

RPS6KA4(Ab-568)

Immunogen:

Synthesized non-phosphopeptide derived from human MSK2 around the phosphorylation site of threonine 568 (M-Q-T(p)-P-C).

Full name:

ribosomal protein S6 kinase, 90kDa, polypeptide 4

Synonyms：

MSK2; RSK-B

SwissProt:

O75676

WB Predicted band size:

86 kDa

WB Positive control:

RAW264.7 cells treated with UV (5mins) lysate

WB Recommended dilution:

500-3000