Background:

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Applications:

ELISA, WB, IHC

Name of antibody:

NDUFS8

Immunogen:

Fusion protein of human NDUFS8

Full name:

NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa

Synonyms：

TYKY; CI-23k; CI23KD

SwissProt:

O00217

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

24 kDa

WB Positive control:

Jurkat cells, mouse heart and brain tissue

WB Recommended dilution:

500-2000