Background:

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Applications:

ELISA, IHC

Name of antibody:

P2RY12

Immunogen:

Synthetic peptide of human P2RY12

Full name:

purinergic receptor P2Y, G-protein coupled, 12

Synonyms：

HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)

SwissProt:

Q9H244

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

10-50