Background:

This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.

Applications:

ELISA, WB

Name of antibody:

NFKB2

Immunogen:

Synthetic peptide of human NFKB2

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Synonyms：

p52, p105, H2TF1, LYT10, LYT-10, NF-kB2

SwissProt:

Q00653

ELISA Recommended dilution:

2000-10000

WB Predicted band size:

97 kDa

WB Positive control:

HT-29 and SKOV3 cells

WB Recommended dilution:

1000-5000