Background:

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0domain. Minor subunit located with subunit a in the membrane (By similarity).

Applications:

WB

Name of antibody:

MT-ATP8

Immunogen:

Synthetic peptide of human MT-ATP8

Full name:

mitochondrially encoded ATP synthase 8

Synonyms:

ATPase8; MTATP8; ATP8

SwissProt:

P03928

WB Predicted band size:

8 kDa

WB Positive control:

Jurkat whole cell lysates

WB Recommended dilution:

500-100