Background:

The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Applications:

ELISA, WB, IHC

Name of antibody:

PBXIP1

Immunogen:

Fusion protein of human PBXIP1

Full name:

PBX homeobox interacting protein 1

Synonyms:

HPIP

SwissProt:

Q96AQ6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

81 kDa

WB Positive control:

PC3, A549 and Hela cell lysates

WB Recommended dilution:

200-1000