Background:

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.

Applications:

ELISA, WB, IHC

Name of antibody:

PAFAH2

Immunogen:

Synthetic peptide of human PAFAH2

Full name:

platelet-activating factor acetylhydrolase 2, 40kDa

Synonyms：

HSD-PLA2

SwissProt:

Q99487

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

44 kDa

WB Positive control:

231 and Jurkat cells

WB Recommended dilution:

200-1000