Background:

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

WB

Name of antibody:

PDE4C

Immunogen:

Synthesized peptide derived from internal of human PDE4C.

Full name:

phosphodiesterase 4C, cAMP-specific

Synonyms：

DPDE1

SwissProt:

Q08493

WB Predicted band size:

80 kDa

WB Positive control:

A549 cells, RAW264.7 cells and Huvec cells lysates

WB Recommended dilution:

500-3000