Background:

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

TLK1

Immunogen:

Synthesized peptide derived from internal of human TLK1.

Full name:

tousled-like kinase 1

Synonyms：

PKU-beta

SwissProt:

Q9UKI8

WB Predicted band size:

87 kDa

WB Positive control:

Rat brain tissue and NIH/3T3 cells lysates

WB Recommended dilution:

500-3000