Background:

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Applications:

ELISA, IHC

Name of antibody:

NTF3

Immunogen:

Fusion protein of human NTF3

Full name:

neurotrophin 3

Synonyms:

NT3; HDNF; NGF2; NT-3; NGF-2

SwissProt:

P20783

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

250-500