Background:

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

POFUT1

Immunogen:

Fusion protein of human POFUT1

Full name:

protein O-fucosyltransferase 1

Synonyms:

DDD2; FUT12; O-FUT; OFUCT1; O-Fuc-T; O-FucT-1

SwissProt:

Q9H488

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human tonsil

IHC Recommend dilution:

50-200