Background:

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Applications:

ELISA, IHC

Name of antibody:

RHEB

Immunogen:

Fusion protein of human RHEB

Full name:

Ras homolog enriched in brain

Synonyms：

RHEB2

SwissProt:

Q15382

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain

IHC Recommend dilution:

10-50