Background:

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus.

Applications:

WB, IHC, IF

Name of antibody:

NR3C1(Ab-211)

Immunogen:

Synthesized non-phosphopeptide derived from human GR around the phosphorylation site of serine 211 (N-E-S-P-W).

Full name:

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms：

GR; GCR; GRL; GCCR; GCRST

SwissProt:

P04150

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

86 kDa

WB Positive control:

Hela cells treated with PMA (125ng/ml, 30min) lysate

WB Recommended dilution:

500-3000

IF positive control:

A549 cells

IF Recommend dilution:

100-500