Background:

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form.

Applications:

ELISA, IHC

Name of antibody:

SORT1

Immunogen:

Synthetic peptide of human SORT1

Full name:

sortilin 1

Synonyms：

NT3; Gp95; LDLCQ6

SwissProt:

Q99523

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human breast cancer

IHC Recommend dilution:

40-150