Background:

May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).

Applications:

ELISA, WB, IHC

Name of antibody:

RAB38

Immunogen:

Fusion protein of human RAB38

Full name:

RAB38, member RAS oncogene family

Synonyms:

rrGTPbp; NY-MEL-1

SwissProt:

P57729

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human prostate cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

24 kDa

WB Positive control:

NIH/3T3 cell lysate

WB Recommended dilution:

500-2000