Background:

This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

PTP4A3

Immunogen:

Fusion protein of human PTP4A3

Full name:

protein tyrosine phosphatase type IVA, member 3

Synonyms:

PRL3; PRL-3; PRL-R

SwissProt:

O75365

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

40-200