Background:

This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

Applications:

ELISA, WB, IHC

Name of antibody:

SEC11A

Immunogen:

Fusion protein of human SEC11A

Full name:

SEC11 homolog A, signal peptidase complex subunit

Synonyms:

SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik

SwissProt:

P67812

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

21 kDa

WB Positive control:

TM4, HEPG2 and A549 cell, Mouse liver tissue lysates

WB Recommended dilution:

500-2000