Background:

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.

Applications:

ELISA, IHC

Name of antibody:

NDUFA1

Immunogen:

Fusion protein of human NDUFA1

Full name:

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

Synonyms：

MWFE; ZNF183; CI-MWFE

SwissProt:

O15239

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human brain

IHC Recommend dilution:

50-200