Background:

Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of α/β Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.

Applications:

ELISA, WB, IHC

Name of antibody:

TBCB

Immunogen:

Full length fusion protein

Full name:

tubulin folding cofactor B

Synonyms:

CG22; CKAP1; CKAPI

SwissProt:

Q99426

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

27 kDa

WB Positive control:

Human cerebrum tissue lysate

WB Recommended dilution:

500-2000