Background:

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23

Applications:

ELISA, IHC

Name of antibody:

USP11

Immunogen:

Synthetic peptide corresponding to a region derived from 951-963 amino acids of human USP11

Full name:

ubiquitin specific peptidase 11

Synonyms:

UHX1

SwissProt:

P51784

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human thyroid cancer;Human gastric cancer

IHC Recommended dilution:

20-100