Background:

The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.

Applications:

ELISA, IHC

Name of antibody:

TWIST2

Immunogen:

Full length of human TWIST2

Full name:

twist family bHLH transcription factor 2

Synonyms：

FFDD3; DERMO1; SETLSS; bHLHa39

SwissProt:

Q8WVJ9

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100