Background:

This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

GJB1

Immunogen:

Synthetic peptide of human GJB1

Full name:

gap junction protein, beta 1, 32kDa

Synonyms：

CMTX; CX32; CMTX1

SwissProt:

P08034

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100