Background:

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

GALT

Immunogen:

Fusion protein of human GALT

Full name:

galactose-1-phosphate uridylyltransferase

SwissProt:

P07902

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil and Human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

43 kDa

WB Positive control:

Human fetal liver tissue

WB Recommended dilution:

500-2000