Background:

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

Applications:

ELISA, WB

Name of antibody:

GALR1

Immunogen:

Synthetic peptide of human GALR1

Full name:

galanin receptor 1

Synonyms:

GALNR; GALNR1

SwissProt:

P47211

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

39 kDa

WB Positive control:

K562 and 293T cell lysates

WB Recommended dilution:

500-2000