Background:

This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.

Applications:

ELISA, IHC

Name of antibody:

GALNT12

Immunogen:

Fusion protein of human GALNT12

Full name:

polypeptide N-acetylgalactosaminyltransferase 12

Synonyms:

CRCS1; GalNAc-T12

SwissProt:

Q8IXK2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300