Background:

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

GALC

Immunogen:

Synthetic peptide of human GALC

Full name:

galactosylceramidase

SwissProt:

P54803

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

77 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

200-1000