Background:

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

GABRG2

Immunogen:

Synthetic peptide of human GABRG2

Full name:

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Synonyms：

CAE2; ECA2; GEFSP3

SwissProt:

P18507

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

54 kDa

WB Positive control:

Mouse brain and human fetal brain tissue

WB Recommended dilution:

500-2000